Antigen Presentation
3D Animation
Media: Cinema 4D, Redshift, Adobe After Effects
Audience: Undergraduate biology students
The purpose of this animation is to educate college students on antigen presentation, specifically focusing on the role of dendritic cells. This process is an essential step of the immune response in the body because it can activate T cells using MHC class II molecules. This animation helps to identify the two types of MHC molecules known as MHC class I and MHC class II and differentiate the cells that primarily express them. Specifically, it highlights the role of dendritic cells and MHC class II in antigen presentation, starting with the ingestion of an external pathogen and leading to T cell recognition.
Pre-Production
Preliminary research on the adaptive immune response, antigen presentation, and the proteins involved in this process took place. The key players in this animation would be dendritic cells, CD4+ T helper cells, and MHC II molecules. After writing a script based on these concepts, a preliminary storyboard was developed and reviewed.
Production
An animatic was developed to get an overall sense of the pacing, camera and object movements in each scene.
Materials and lighting were added to the final 3D models of the key players that were incorporated in each scene.
Post-Production
Specific labels, protein call-outs, audio and background environment effects were added using Adobe After Effects.
